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National Center for Biotechnology InformationU. The first group comprised 19 gay men who had died of AIDS -related illnesses. However, no field of research subject to this debate generates more heated controversies than those probing the proximate causes of sexual orientation, particularly its less-frequent and thus, perhaps, more-perplexing form: The causes of a trait should not influence how we see it. Note, however, that this mechanism potentially explains only a fraction of gay males, so other mechanisms must also be at work. Genes, Brain and Behavior.

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In addition to sex chromosomal contribution, a potential autosomal genetic contribution to the development of homosexual orientation has also been suggested.

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'Gay genes': science is on the right track, we're born this way. Let’s deal with it.

Since the hypothesis solves the problem of why homosexuality has not been selected out over thousands of years, despite it being antithetical to reproduction, many scientists consider it the best explanatory model for non-heterosexual behaviour such as homosexuality and bisexuality. Ward thinks this question is the next frontier of queer thought. The inactivation of the X chromosome occurs randomly throughout the embryo, resulting in cells that are mosaic with respect to which chromosome is active. The genetics of sex differences in brain and behavior. View image of Credit: Homosexuality as a consequence of epigenetically canalized sexual development.

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Retrieved 19 March Views Read Edit View history. However, none of the four variants could reliably predict sexual orientation. Is There a Role for Epigenetics? The "gay uncle hypothesis" posits that people who themselves do not have children may nonetheless increase the prevalence of their family's genes in future generations by providing resources e.

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